| Title Holder | Tenure | Status | Def | Birthplace | Notes |
| Shane Mosley * | 2009- | WBA | 0 | USA | |
| Andre Berto | 2009- | WBC | 3 | USA | |
| Manny Pacquiao | 2009- | WBO | 0 | Philippines | |
| Pacquiao makes Boxing History winning a title in a record seventh weight division. | |||||
| Jan Zaveck | 2009- | IBF | 0 | Slovenia | |
| Vyacheslav Senchenko | 2009- | WBA | 0 | Ukraine | |
| Miguel Cotto | 2009 | WBO | 1 | Puerto rico | |
| Isaac Hlatshwayo | 2009 | IBF | 0 | S. Africa | |
| Antonio Margarito | 2008-2009 | WBA | 0 | Mexico | |
| Carlos Quintana | 2008 | WBO | 0 | Puerto Rico | |
| Antionio Margarito | 2008 | IBF | 0 | Mexico | |
| Miguel Angel Cotto | 2008 | WBA | 0 | Puerto Rico | |
| Yuriy Nuzhnenko | 2008 | WBA | 0 | Ukraine | |
| Paul Williams | 2008 | WBO | 0 | USA | Williams vacated the title. |
| Joshua Clottey | 2008 | IBF | 0 | Ghana | |
| Paul Williams | 2007-2008 | WBO | 0 | USA | |
| Yuriy Nuzhnenko | 2007-2008 | WBA | 0 | Ukraine | |
| Shane Mosley | 2007 | WBC | 0 | USA | |
| Floyd Mayweather | 2007 | WBC | 0 | USA | |
| Floyd Mayweather | 2006-2008 | WBC | 0 | USA | Mayweather vacated title to fight in a Lt-Middleweight bout |
| Miguel Angel Cotto | 2006-2008 | WBA | 3 | Puerto Rico | |
| Kermit Cintron | 2006-2008 | IBF | 2 | USA | |
| Carlos Baldomir | 2006 | WBC | 1 | Argentina | |
| Floyd Mayweather | 2006 | IBF | 0 | USA | Mayweather vacated title to challenge for the WBC version. |
| Ricky Hatton | 2006 | WBA | 0 | England | Hatton relinquished title to defend his Lt-Welterweight title. |
| Antonio Margarito | 2005-2007 | WBO | 3 | ||
| Zab Judah | 2005-2006 | IBF-WBA-WBC | 1 | USA | |
| Luis Collazo | 2005 | WBA | 1 | USA | |
| Kermit Cintron | 2004 | WBO | 0 | USA | |
| Cory Spinks | 2003-2005 | IBF-WBA-WBC | 2 | USA | |
| Ricardo Mayorga | 2003 | WBA-WBC | 1 | Nicaragua | |
| Cory Spinks | 2003 | IBF | 3 | USA | |
| Ricardo Mayorga | 2002-2003 | WBA | 1 | Nicaragua | |
| Michele Piccirillo | 2002-2003 | IBF | 0 | Italy | |
| Antonio Margarito | 2001-2004 | WBO | 4 | Mexico | |
| Vernon Forrest | 2001-2003 | WBC | 1 | USA | |
| Andrew Lewis | 2001-2002 | WBA | 2 | Guyana | |
| Vernon Forrest | 2001 | IBF | 1 | USA | |
| Daniel Santos | 2000-2002 | WBO | 3 | Puerto Rico | Santos relinquished title and moved to Light Middleweight. |
| Shane Mosley | 2000-2002 | WBC | 3 | USA | |
| Oscar De La Hoya | 2000 | WBC | 0 | USA | After Trinidad vacated title WBC reinstated De La Hoya. |
| Felix Trinidad | 1999-2000 | IBF-WBC | 0 | Puerto Rico | Trinidad unified titles but vacated to move to Light middleweight. |
| Ahmed Kotiev | 1998-2000 | WBO | 4 | Russia | Also knowen as Ahmed Katajev. |
| James Page | 1998-2000 | WBA | 3 | USA | Page was stripped of title. |
| Oscar De La Hoya | 1997-1999 | WBC | 7 | USA | |
| Michael Loewe | 1997-1998 | WBO | 1 | Romania | Loewe relinquished title due to injury. |
| Jose Luis Lopez | 1996-1997 | WBO | 1 | Mexico | Lopez stripped of title after failing a drugs test. |
| Ike Quartey | 1994-1998 | WBA | 7 | Ghana | Quartey stripped of title. |
| Felix Trinidad | 1993-2000 | IBF | 15 | Puerto Rico | |
| Pernell Whitaker | 1993-1997 | WBC | 8 | USA | |
| Eamonn Loughran | 1993-1996 | WBO | 5 | Ireland | |
| Gert Bo Jacobsen | 1993 | WBO | 0 | Denmark | Jacobsen relinquised title. |
| Crisano Espana | 1992-1994 | WBA | 2 | Venezuela | |
| Maurice Blocker | 1991-1993 | IBF | 1 | USA | |
| James Buddy McGrit | 1991-1993 | WBC | 2 | USA | |
| Meldrick Taylor | 1991-1992 | WBA | 2 | USA | |
| Simon Brown | 1991 | WBC | 0 | Jamaica | |
| Aaron Davis | 1990-1991 | WBA | 0 | USA | |
| Maurice Blocker | 1990-1991 | WBC | 0 | USA | |
| Manning Galloway | 1989-1993 | WBO | 7 | USA | |
| Mark Breland | 1989-1990 | WBA | 4 | USA | |
| Marlon Starling | 1989-1990 | WBC | 1 | USA | |
| Genaro Leon | 1989 | WBO | 0 | Mexico | Leon relinquished the WBO title. |
| Simon Brown | 1988-1991 | IBF | 7 | Jamaica | Brown vacated IBF title to challenge for WBC version. |
| Lloyd Honeyghan | 1988-1989 | WBC | 2 | Jamaica | |
| Tomas Molinares | 1988-1989 | WBA | 0 | Colombia | Molinares was stripped of title for failer to make the weight. |
| Marlon Starling | 1987-1988 | WBA | 2 | USA | |
| Jorge Vaca | 1987-1988 | WBC | 0 | Mexico | IBF stripped Vaca as defence was not to their rules. |
| Mark Breland | 1987 | WBA | 0 | USA | |
| Lloyd Honeyghan | 1986-1987 | WBC-IBF | 2 | Jamaica | |
| Lloyd Honeyghan | 1986 | Undisputed | 0 | Jamaica | Honeyghan relinquished WBA title to defend WBC and IBF titles. |
| Don Curry | 1985-1986 | Undisputed | 1 | USA | |
| Don Curry | 1984-1985 | WBA-IBF | 2 | USA | |
| Milton McCrory | 1983-1985 | WBC | 5 | USA | |
| Don Curry | 1983-1984 | WBA | 3 | USA | |
| Sugar Ray Leonard | 1981-1982 | Undisputed | 0 | USA | Leonard retired as undisputed Welterweight champion. |
| Thomas Hearns | 1980-1981 | WBA | 3 | USA | |
| Sugar Ray Leonard | 1980-1981 | WBC | 1 | USA | |
| Roberto Duran | 1980 | WBC | 0 | Panama | |
| Sugar Ray Leonard | 1979-1980 | WBC | 1 | USA | |
| Wilfred Benitez | 1979 | WBC | 1 | USA | |
| Pipino Cuevas | 1976-1980 | WBA | 11 | Mexico | |
| Carlos Palomino | 1976-1979 | WBC | 7 | Mexico | |
| Angel Espada | 1975-1976 | WBA | 1 | Puerto Rico | |
| John H Stracey | 1975-1976 | WBC | 1 | England | |
| Jose Napoles | 1975 | WBC | 1 | Cuba | |
| Jose Napoles | 1974-1975 | Undisputed | 2 | Cuba | Napoles relinquished WBA title to defend the WBC version. |
| Jose Napoles | 1972-1974 | WBA-WBC | 0 | Cuba | The NY commission stripped Napoles for failing to defend. |
| Hedgemon Lewis | 1972-1974 | NY | 1 | USA | |
| Jose Napoles | 1971-1972 | NY | 1 | Cuba | |
| Billy Backus | 1970-1971 | Undisputed | 0 | USA | |
| Jose Napoles | 1969-1970 | Undisputed | 3 | Cuba | |
| Curtis Cokes | 1966-1967 | Undisputed | 5 | USA | |
| Curtis Cokes | 1966 | WBA | 0 | USA | |
| Emile Griffith | 1963-1966 | Undisputed | 4 | Virgin Islands | Griffith relinquished title on becoming Middleweight Champion. |
| Luis Rodriguez | 1963 | Undisputed | 0 | Cuba | |
| Emile Griffith | 1962-1963 | Undisputed | 2 | Virgin Island | |
| Benny Kid Paret | 1961-1962 | Undisputed | 0 | Cuba | |
| Emile Griffith | 1961 | Undisputed | 1 | Virgin Island | |
| Benny Kid Pare | 1960-1961 | Undisputed | 1 | Cuba | |
| Don Jordan | 1958-1960 | Undisputed | 2 | Dominican Rep | |
| Virgil Akins | 1958 | Undisputed | 0 | USA | |
| Carmen Basilio | 1956-1957 | Undisputed | 1 | USA | Basilio relinquished title on winning Undisputed Middleweight title. |
| Johnny Saxton | 1956 | Undisputed | 0 | USA | |
| Carmen Basilio | 1955-1956 | Undisputed | 1 | USA | |
| Tony De Marco | 1955 | Undisputed | 0 | USA | |
| Johnny Saxton | 1954-1955 | Undisputed | 0 | USA | |
| Kid Gavlin | 1952-1954 | Undisputed | 7 | Cuba | |
| Kid Gavlin | 1951-1952 | NBA-NY | 0 | Cuba | |
| Johhny Bratton | 1951 | NBA | 0 | USA | |
| Sugar Ray Robinson | 1946-1951 | NY-NBA | 0 | USA | Robinson relinquished titles on becoming Middleweight Champion. |
| Marty Servo | 1946 | NY-NBA | 5 | USA | Servo announced his retirment. |
| Red Chochrane | 1942-1946 | 0 | USA | ||
| Red Cochrane | 1941-1942 | NY-NBA | 0 | USA | |
| Fritzie Zivic | 1940-1941 | NY-NBA | 0 | USA | |
| Fritzie Zivic | 1940 | Undisputed | 1 | USA | |
| Henry Armstrong | 1938-1940 | Undisputed | 19 | USA | Armstrong also defended his Lightweight title during this reign. |
| Barnie Ross | 1938 | NY-NBA | 0 | USA | The IBU withdrew recognition of Ross as Champion. |
| Felix Wouters | 1938 | IBU | 0 | Belgium | |
| Barnie Ross | 1938 | IBU | 0 | USA | |
| Barnie Ross | 1935-1938 | Undisputed | 2 | USA | |
| Jimmy McLarnin | 1934-1935 | Undisputed | 0 | Ireland | |
| Barnie Ross | 1934 | Undisputed | 0 | USA | |
| Jimmy McLarnin | 1933-1934 | Undisputed | 0 | Ireland | |
| Young Corbett III | 1933 | Undisputed | 0 | Italy | |
| Jackie Fields | 1932-1933 | Undisputed | 0 | USA | |
| Lou Brouillard | 1931-1932 | Undisputed | 0 | Canada | |
| Tommy Freeman | 1930-1931 | Undisputed | 0 | USA | |
| Young Jack Thompson | 1930 | Undisputed | 0 | USA | |
| Young Jack Thompson | 1930 | Undisputed | 0 | USA | |
| Jackie Fields | 1929-1930 | Undisputed | 0 | USA | |
| Jackie Fields | 1929 | NBA | 1 | USA | |
| Joe Dundee | 1928-1929 | NY | 0 | Italy | |
| Joe Dundee | 1927-1928 | NY-NBA | 1 | Italy | NBA stripped Dundee for failing to defend. |
| Pete Latzo | 1926-1927 | NY | 1 | USA | |
| Mickey Walker | 1924-1926 | NY | 2 | USA | |
| Mickey Walker | 1923-1924 | NBA | 0 | USA | Walker was stripped of title for failer to defend. |
| Dave Shade | 1923 | NY | 0 | USA | |
| Jimmy Jones | 1923 | NY | 0 | USA | The NY Commision stripped Jones of title. |
| Jack Britton | 1919-1922 | 5 | USA | ||
| Ted Kid Lewis | 1917-1919 | 1 | England | ||
| Jack Britton | 1916-1917 | 2 | USA | ||
| Waldemer Holberg | 1914 | AUST | 0 | Denmark | |
| Tom McCormick | 1914 | AUST | 0 | England | |
| Matt Wells | 1914 | AUST | 0 | England | |
| Mike Glover | 1913-1915 | 1 | USA | ||
| Marcel Thomas | 1912-1913 | IBU | 0 | France | |
| Dixie Kid | 1911-1912 | 1 | USA | ||
| Harry Lewis | 1910-1911 | 3 | USA | Lewis relinquished title to box at Middleweight. | |
| Mike Twin Sullivan | 1907-1908 | 0 | USA | Sullivan vacated title due to weight problems. | |
| Honey Mellody | 1906-1907 | 0 | USA | ||
| Joe Walcott | 1901-1906 | 4 | Barbados | ||
| Jim Ferns | 1901 | 1 | USA | ||
| Matty Mathews | 1900-1901 | 1 | USA | ||
| Matty Matthews | 1900 | 0 | USA | ||
| Eddie Connolly | 1900 | 0 | Canada | ||
| Jim Ferns | 1900 | 0 | USA | ||
| Mysterious Bill Smith | 1898-1900 | 3 | USA | ||
| Joe Walcott | 1897-1898 | 0 | Barbados | ||
| GeorgeGreen | 1897 | 0 | USA | ||
| Tommy Ryan | 1894-1897 | 2 | USA | ||
| Mysterious Bill Smith | 1892-1894 | 1 | USA | ||
| Tommy Ryan | 1891-1892 | 1 | USA | ||
| Paddy Duffy | 1889-1890 | 1 | USA | Duffy died and Tommy Ryan claimed the title. | |
| Bold ( Indicates Current Holder) - Bold (Indicates Undisputed) - * (Indicates WBA Super) | |||||